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IGF-1 LR3 Nasal Spray certificate of analysis, lot PL-2610-100

Certificate PL-26-00214 reports the release tests for IGF-1 LR3 Nasal Spray lot PL-2610-100: 99.31% purity by reverse-phase HPLC and identity confirmed by LC-MS, tested October 6, 2026. The lot number printed on each unit matches this certificate.

Certificate numberPL-26-00214
Lot numberPL-2610-100
CompoundIGF-1 LR3 Nasal Spray 1 mg
SequenceH-MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA-OH (83 residues; three intrachain disulfides; free N- and C-termini)
Molecular formulaC 400 H 625 N 111 O 115 S 9 (reduced-chain calculation)
CAS number143045-27-6
Purity (RP-HPLC)99.31%
Identity (LC-MS)Conforms (9,111.46 Da) · expected 9111.6 Da, found 9111.46 Da
MethodRP-HPLC (UV 214 nm) + LC-MS
TestedOctober 6, 2026
Retest byOctober 5, 2028
Tested byManufacturer’s in-house laboratory (not an independent third-party test)
ConclusionConforms

Tests run on this lot

TestMethodSpecificationResult
Identity (mass)LC-MS, ESI positiveTheoretical ± 1.0 Da9,111.46 Da (PASS)
PurityRP-HPLC, UV 214 nm, area%≥ 99.0%99.31% (PASS)
Largest impurityRP-HPLC, area%≤ 1.0%0.36% (RT 14.50) (PASS)
Assay (label claim)Assay vs label claim1.9–2.1 mg/bottle1.95 mg/bottle (PASS)
Bacterial endotoxinLAL, kinetic≤ 5.0 EU/mg0.134 EU/mg (PASS)
Aerobic count (TAMC)USP <61>< 10 CFU/mL< 10 CFU/mL (PASS)
Yeast & mold (TYMC)USP <61>< 10 CFU/mL< 10 CFU/mL (PASS)
E. coliUSP <62>AbsentAbsent (PASS)

What these results mean

HPLC purity is the share of UV-detectable material that elutes as the target compound; it is not the same as net peptide content, which also accounts for water and counter-ions. Identity means the measured mass matched the mass calculated for the compound. A certificate reports only the tests run on this lot; endotoxin, sterility and contaminant panels are not part of standard lot release. How to read a certificate of analysis.

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