MOTS-c Pen certificate of analysis, lot PL-2610-131
Certificate PL-26-00245 reports the release tests for MOTS-c Pen lot PL-2610-131: 99.71% purity by reverse-phase HPLC and identity confirmed by LC-MS, tested October 6, 2026. The lot number printed on each unit matches this certificate.
| Certificate number | PL-26-00245 |
|---|---|
| Lot number | PL-2610-131 |
| Compound | MOTS-c Pen 30 mg |
| Sequence | H-MRWQEMGYIFYPRKLR-OH (16 residues; free N- and C-termini) |
| Molecular formula | C101H152N28O22S2 |
| CAS number | 1627580-64-6 |
| Purity (RP-HPLC) | 99.71% |
| Identity (LC-MS) | Conforms (2,174.69 Da) · expected 2174.6 Da, found 2174.69 Da |
| Method | RP-HPLC (UV 214 nm) + LC-MS |
| Tested | October 6, 2026 |
| Retest by | October 5, 2028 |
| Tested by | Manufacturer’s in-house laboratory (not an independent third-party test) |
| Conclusion | Conforms |
Tests run on this lot
| Test | Method | Specification | Result |
|---|---|---|---|
| Identity (mass) | LC-MS, ESI positive | Theoretical ± 1.0 Da | 2,174.69 Da (PASS) |
| Purity | RP-HPLC, UV 214 nm, area% | ≥ 99.0% | 99.71% (PASS) |
| Largest impurity | RP-HPLC, area% | ≤ 1.0% | 0.16% (RT 13.30) (PASS) |
| Assay (label claim) | Assay vs label claim | 9.5–10.5 mg/mL | 10.07 mg/mL (PASS) |
| Bacterial endotoxin | LAL, kinetic | ≤ 5.0 EU/mg | 0.478 EU/mg (PASS) |
| Sterility | USP <71>, 14-day | No growth | No growth (PASS) |
What these results mean
HPLC purity is the share of UV-detectable material that elutes as the target compound; it is not the same as net peptide content, which also accounts for water and counter-ions. Identity means the measured mass matched the mass calculated for the compound. A certificate reports only the tests run on this lot; endotoxin, sterility and contaminant panels are not part of standard lot release. How to read a certificate of analysis.
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