Semaglutide certificate of analysis, lot PL-2610-184
Certificate PL-26-00297 reports the release tests for Semaglutide lot PL-2610-184: 99.15% purity by reverse-phase HPLC and identity confirmed by LC-MS, tested October 9, 2026. The lot number printed on each unit matches this certificate.
| Certificate number | PL-26-00297 |
|---|---|
| Lot number | PL-2610-184 |
| Compound | Semaglutide 30 mg |
| Sequence | H-H-Aib-EGTFTSDVSSYLEGQAAK(2×OEG-γGlu-C18 diacid)EFIAWLVRGRG-OH (31 residues; Aib8 and Arg34 in GLP-1 numbering; Lys26 acylated with octadecanedioic acid via two OEG spacers and γ-Glu; free C-terminus) |
| Molecular formula | C187H291N45O59 |
| CAS number | 910463-68-2 |
| Purity (RP-HPLC) | 99.15% |
| Identity (LC-MS) | Conforms (4,113.34 Da) · expected 4113.58 Da, found 4113.34 Da |
| Method | RP-HPLC (UV 214 nm) + LC-MS |
| Tested | October 9, 2026 |
| Retest by | October 7, 2028 |
| Tested by | Manufacturer’s in-house laboratory (not an independent third-party test) |
| Conclusion | Conforms |
Tests run on this lot
| Test | Method | Specification | Result |
|---|---|---|---|
| Identity (mass) | LC-MS, ESI positive | Theoretical ± 1.0 Da | 4,113.34 Da (PASS) |
| Purity | RP-HPLC, UV 214 nm, area% | ≥ 99.0% | 99.15% (PASS) |
| Largest impurity | RP-HPLC, area% | ≤ 1.0% | 0.30% (RT 7.27) (PASS) |
| Water content | Karl Fischer | ≤ 5.0% | 2.42% (PASS) |
| Bacterial endotoxin | LAL, kinetic | ≤ 5.0 EU/mg | 0.050 EU/mg (PASS) |
| Sterility | USP <71>, 14-day | No growth | No growth (PASS) |
What these results mean
HPLC purity is the share of UV-detectable material that elutes as the target compound; it is not the same as net peptide content, which also accounts for water and counter-ions. Identity means the measured mass matched the mass calculated for the compound. A certificate reports only the tests run on this lot; endotoxin, sterility and contaminant panels are not part of standard lot release. How to read a certificate of analysis.
Semaglutide · Verify this certificate · All certificates
Other Semaglutide lots
- PL-26-00296, lot PL-2610-183, 99.48%, tested October 9, 2026
- PL-26-00295, lot PL-2610-182, 99.55%, tested October 7, 2026
- PL-26-00294, lot PL-2610-181, 99.36%, tested October 7, 2026
- PL-26-00293, lot PL-2610-180, 99.13%, tested October 7, 2026
- PL-26-00094, lot PL-2609-094, 99.35%, tested September 19, 2026
- PL-26-00093, lot PL-2609-093, 99.27%, tested September 19, 2026
- PL-26-00092, lot PL-2609-092, 99.31%, tested September 19, 2026
- PL-26-00091, lot PL-2609-091, 99.24%, tested September 19, 2026
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