Prostamax Pen
20 mg of the Khavinson prostate tetrapeptide in 3 mL of bacteriostatic water at 0.67% w/v. Filled from a peptide lot tested in the manufacturer’s own laboratory, with a certificate.
| Compound | Prostamax Lys-Glu-Asp-Pro (KEDP); Khavinson prostate peptide bioregulator |
|---|---|
| CAS number | Not assigned |
| Molecular formula | C20H33N5O9 |
| Theoretical mass | 487.5 Da |
| Sequence / structure | H-KEDP-OH (4 residues; free N- and C-termini) |
| Contents | Prostamax: 20 mg per 3 mL pen (0.67% w/v) |
| Form | Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a 3 mL glass cartridge inside a preloaded autoinjector pen fitted with a needle |
| Storage, sealed | Store at 2–8 °C in the original carton, protected from light |
| Format | Solution in a 3 mL pre-filled pen |
Sizes and lots
- 20 mg · 1 pen — $88.99
- 20 mg · Kit of 10 — $791.12
Prostamax is the Khavinson tetrapeptide Lys-Glu-Asp-Pro (KEDP), linked by its developers to the prostate. This listing is a preloaded pen whose 3 mL cartridge holds 20 mg of Prostamax in solution, the same amount as the freeze-dried vial. Published work naming Prostamax is limited, comes mostly from one St Petersburg group, and centres on chromatin structure and the idea that short peptides regulate genes.
What is in the pen
The pen contains a 3 mL glass cartridge of sterile aqueous solution with Prostamax at 0.67% w/v, 20 mg per pen. At the certificate's theoretical mass of 487.5 Da, that is about 41 µmol. The solvent is bacteriostatic water with 0.9% benzyl alcohol as an antimicrobial preservative. The safety data sheet lists no hazard class for the peptide; benzyl alcohol is harmful if swallowed or inhaled, irritates the eyes seriously and may cause an allergic skin reaction.
Store the pen at 2 to 8 °C in its carton, shielded from light, and keep it capped between uses. Freezing is not allowed: a pen whose solution has frozen, discoloured or gone cloudy should be thrown away. The Prostamax 20 mg vial holds the same amount as dry powder, and peptide pen vs vial explains the general differences.
What the research covers
The one experimental paper among these references that names Prostamax measured chromatin in leukocytes from people aged 75 to 881. With four other short peptides, Prostamax activated ribosomal genes and decondensed tightly packed chromatin, and with Epitalon and Livagen it also loosened structural heterochromatin near the centromere of chromosome 11. Epitalon and Livagen went on to change chromosome 9 as well, and Prostamax did not1. The abstract gives no number of donors and no effect sizes. The study came from the programme's own group and was published in the Bulletin of Experimental Biology and Medicine, which carries Russian research in English. The developers interpret findings like these through a model in which peptides of two to seven residues act on histones, DNA and DNA methylation inside the nucleus2.
Nothing in that work concerns Prostamax in solution. No published study cited here measured how KEDP holds up in bacteriostatic water at 2 to 8 °C, and none used a pen or any preloaded format, so the storage limits for this pen come from its safety data sheet. The Prostamax 20 mg vial page has the full research summary, and the Prostamax guide covers the prostate explant work and the compound's origins.
Frequently asked questions
How does the Prostamax pen compare with the vial?
Both contain 20 mg of the same tetrapeptide. The vial holds it as freeze-dried powder at −20 °C for dissolving in the lab; the pen holds it already dissolved in 3 mL of bacteriostatic water at 0.67% w/v, stored at 2 to 8 °C and never frozen.
Do the published Prostamax studies apply to the pen?
Only as background on the compound. The chromatin study and the reviews describe the peptide in cells, not in a stored solution, and none reports its stability in bacteriostatic water. Follow the safety data sheet for the pen's storage.
References
- Khavinson VKh, Lezhava TA, Malinin VV. Effects of short peptides on lymphocyte chromatin in senile subjects. Bull Exp Biol Med. 2004;137(1):78-81. DOI · PubMed
- Khavinson VK, Popovich IG, Linkova NS, et al. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22). DOI · PubMed
For laboratory research use only. Not for human or veterinary consumption. Products have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease.